GUCY1A2 explained

Guanylate cyclase soluble subunit alpha-2 is an enzyme that in humans is encoded by the GUCY1A2 gene.^{[1] [2]}

Further reading

• Baba H, Suzuki T, Arai H, Emson PC . Expression of nNOS and soluble guanylate cyclase in schizophrenic brain . NeuroReport . 15 . 4 . 677–80 . 2004 . 15094474 . 10.1097/00001756-200403220-00020 . 45536193 .
• Bellamy TC, Wood J, Garthwaite J . On the activation of soluble guanylyl cyclase by nitric oxide . Proc. Natl. Acad. Sci. U.S.A. . 99 . 1 . 507–10 . 2002 . 11752394 . 10.1073/pnas.012368499 . 117590 . 2002PNAS...99..507B . free .
• Russwurm M, Wittau N, Koesling D . Guanylyl cyclase/PSD-95 interaction: targeting of the nitric oxide-sensitive alpha2beta1 guanylyl cyclase to synaptic membranes . J. Biol. Chem. . 276 . 48 . 44647–52 . 2002 . 11572861 . 10.1074/jbc.M105587200 . free .
• Bamberger AM . Expression and tissue localization of soluble guanylyl cyclase in the human placenta using novel antibodies directed against the alpha(2) subunit . J. Clin. Endocrinol. Metab. . 86 . 2 . 909–12 . 2001 . 11158065 . vanc. Koglin M . Kempfert J . 3 . Löning . T . Scholz . H . Behrends . S . 10.1210/jcem.86.2.7409 . free.
• Budworth J, Meillerais S, Charles I, Powell K . Tissue distribution of the human soluble guanylate cyclases . Biochem. Biophys. Res. Commun. . 263 . 3 . 696–701 . 1999 . 10512742 . 10.1006/bbrc.1999.1444 .
• Yu F, Warburton D, Wellington S, Danziger RS . Assignment of GUCIA2, the gene coding for the alpha 2 subunit of soluble guanylyl cyclase, to position 11q21-q22 on human chromosome 11 . Genomics . 33 . 2 . 334–6 . 1997 . 8660992 . 10.1006/geno.1996.0208 . free .
• Behrends S, Harteneck C, Schultz G, Koesling D . A variant of the alpha 2 subunit of soluble guanylyl cyclase contains an insert homologous to a region within adenylyl cyclases and functions as a dominant negative protein . J. Biol. Chem. . 270 . 36 . 21109–13 . 1995 . 7673142 . 10.1074/jbc.270.36.21109 . free .

Notes and References

1. Harteneck C, Wedel B, Koesling D, Malkewitz J, Bohme E, Schultz G . Molecular cloning and expression of a new alpha-subunit of soluble guanylyl cyclase. Interchangeability of the alpha-subunits of the enzyme . FEBS Lett . 292 . 1–2 . 217–22 . Jan 1992 . 1683630 . 10.1016/0014-5793(91)80871-Y . 84974514 . free .
2. Web site: Entrez Gene: GUCY1A2 guanylate cyclase 1, soluble, alpha 2.