GSK3A explained

Glycogen synthase kinase-3 alpha is an enzyme that in humans is encoded by the GSK3A gene.^[1]

Glycogen synthase kinase 3-alpha is a multifunctional protein serine kinase, homologous to Drosophila 'shaggy' (zeste-white3) and implicated in the control of several regulatory proteins including glycogen synthase and various transcription factors (e.g., JUN). It also plays a role in the WNT and phosphoinositide 3-kinase (especially PIK3CG) signaling pathways.^{[2] [3]}

See also

• Glycogen synthase kinase 3

Notes and References

1. Shaw PC, Davies AF, Lau KF, Garcia-Barcelo M, Waye MM, Lovestone S, Miller CC, Anderton BH . Isolation and chromosomal mapping of human glycogen synthase kinase-3 alpha and -3 beta encoding genes . Genome . 41 . 5 . 720–7 . Oct 1998 . 9809441 . 10.1139/gen-41-5-720 .
2. Ali A, Hoeflich KP, Woodgett JR . Glycogen synthase kinase-3: properties, functions, and regulation . Chemical Reviews . 101 . 8 . 2527–40 . Aug 2001 . 11749387 . 10.1021/cr000110o .
3. Web site: Entrez Gene: GSK3A glycogen synthase kinase 3 alpha.