GRAMD4 explained

GRAM domain containing 4 (GRAMD4) also known as Death-Inducing Protein (DIP) is a protein that is encoded by the GRAMD4 gene.[1] [2]

Function

GRAMD4 is a mitochondrial effector of E2F1 (MIM 189971)-induced apoptosis.[3]

Further reading

Notes and References

  1. Web site: Entrez Gene: GRAM domain containing 4. 2017-05-16.
  2. Web site: RecName: Full=GRAM domain-containing protein 4; AltName: Full=Death-inducing protein. 2020-03-07.
  3. Stanelle J, Tu-Rapp H, Pützer BM . A novel mitochondrial protein DIP mediates E2F1-induced apoptosis independently of p53 . Cell Death Differ. . 12 . 4 . 347–57 . 2005 . 15565177 . 10.1038/sj.cdd.4401532 . 24578301 .