GPR68 explained

Ovarian cancer G-protein coupled receptor 1 is a protein that in humans is encoded by the GPR68 gene.^{[1] [2]}

See also

• Proton-sensing G protein-coupled receptors

Further reading

• Xu Y . Sphingosylphosphorylcholine and lysophosphatidylcholine: G protein-coupled receptors and receptor-mediated signal transduction. . Biochim. Biophys. Acta . 1582 . 1–3 . 81–8 . 2002 . 12069813 . 10.1016/S1388-1981(02)00140-3.
• An S, Tsai C, Goetzl EJ . Cloning, sequencing and tissue distribution of two related G protein-coupled receptor candidates expressed prominently in human lung tissue. . FEBS Lett. . 375 . 1–2 . 121–4 . 1996 . 7498459 . 10.1016/0014-5793(95)01196-L . 9845527 . free .
• Bonaldo MF, Lennon G, Soares MB . Normalization and subtraction: two approaches to facilitate gene discovery. . Genome Res. . 6 . 9 . 791–806 . 1997 . 8889548 . 10.1101/gr.6.9.791 . free .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Ludwig MG, Vanek M, Guerini D, etal . Proton-sensing G-protein-coupled receptors. . Nature . 425 . 6953 . 93–8 . 2003 . 12955148 . 10.1038/nature01905 . 2003Natur.425...93L . 4395698 .
• Bektas M, Barak LS, Jolly PS, etal . The G protein-coupled receptor GPR4 suppresses ERK activation in a ligand-independent manner. . Biochemistry . 42 . 42 . 12181–91 . 2003 . 14567679 . 10.1021/bi035051y .
• Brandenberger R, Wei H, Zhang S, etal . Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. . Nat. Biotechnol. . 22 . 6 . 707–16 . 2005 . 15146197 . 10.1038/nbt971 . 27764390 .
• Gerhard DS, Wagner L, Feingold EA, etal . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
• Radu CG, Nijagal A, McLaughlin J, etal . Differential proton sensitivity of related G protein-coupled receptors T cell death-associated gene 8 and G2A expressed in immune cells. . Proc. Natl. Acad. Sci. U.S.A. . 102 . 5 . 1632–7 . 2005 . 15665078 . 10.1073/pnas.0409415102 . 545089 . 2005PNAS..102.1632R . free .
• Tomura H, Wang JQ, Komachi M, etal . Prostaglandin I(2) production and cAMP accumulation in response to acidic extracellular pH through OGR1 in human aortic smooth muscle cells. . J. Biol. Chem. . 280 . 41 . 34458–64 . 2005 . 16087674 . 10.1074/jbc.M505287200 . free .
• Singh LS, Berk M, Oates R, etal . Ovarian cancer G protein-coupled receptor 1, a new metastasis suppressor gene in prostate cancer. . J. Natl. Cancer Inst. . 99 . 17 . 1313–27 . 2007 . 17728215 . 10.1093/jnci/djm107 . free . 10536/DRO/DU:30094039 . free .

Notes and References

1. Xu Y, Casey G . Identification of human OGR1, a novel G protein-coupled receptor that maps to chromosome 14 . Genomics . 35 . 2 . 397–402 . Sep 1996 . 8661159 . 10.1006/geno.1996.0377 .
2. Web site: Entrez Gene: GPR68 G protein-coupled receptor 68.