GPR26 explained

Probable G-protein coupled receptor 26 is a protein that in humans is encoded by the GPR26 gene.^[1] GPR26 expression is found to peak perinatally, when the visual system is first challenged, and contains a 53 kb LD-block enriched for association with introgressed Neanderthal-derived SNPs. Additionally, it is known to form oligomeric structures with the 5-HT1a receptor.^[2]

Further reading

• Adams MD, Soares MB, Kerlavage AR, Fields C, Venter JC . Rapid cDNA sequencing (expressed sequence tags) from a directionally cloned human infant brain cDNA library . Nature Genetics . 4 . 4 . 373–380 . August 1993 . 8401585 . 10.1038/ng0893-373 . 12612300 .
• Lee DK, Lynch KR, Nguyen T, Im DS, Cheng R, Saldivia VR, Liu Y, Liu IS, Heng HH, Seeman P, George SR, O'Dowd BF, Marchese A . 6 . Cloning and characterization of additional members of the G protein-coupled receptor family . Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression . 1490 . 3 . 311–323 . February 2000 . 10684976 . 10.1016/s0167-4781(99)00241-9 .
• Salim K, Fenton T, Bacha J, Urien-Rodriguez H, Bonnert T, Skynner HA, Watts E, Kerby J, Heald A, Beer M, McAllister G, Guest PC . 6 . Oligomerization of G-protein-coupled receptors shown by selective co-immunoprecipitation . The Journal of Biological Chemistry . 277 . 18 . 15482–15485 . May 2002 . 11854302 . 10.1074/jbc.M201539200 . free .

Notes and References

1. Web site: Entrez Gene: GPR26 G protein-coupled receptor 26.
2. Gregory MD, Kippenhan JS, Eisenberg DP, Kohn PD, Dickinson D, Mattay VS, Chen Q, Weinberger DR, Saad ZS, Berman KF . 6 . Neanderthal-Derived Genetic Variation Shapes Modern Human Cranium and Brain . Scientific Reports . 7 . 1 . 6308 . July 2017 . 28740249 . 5524936 . 10.1038/s41598-017-06587-0 . 2017NatSR...7.6308G .