GPR148 explained

G protein-coupled receptor 148, also known as GPR148, is a human orphan receptor from GPCR superfamily.^[1] It is expressed primarily in nervous system and testis. Is may be implicated in prostate cancer.

Further reading

• Takeda S, Kadowaki S, Haga T . Identification of G protein-coupled receptor genes from the human genome sequence . FEBS Lett. . 520 . 1–3 . 97–101 . 2002 . 12044878 . 10.1016/S0014-5793(02)02775-8 . 7116392 . etal.
• Strausberg RL, Feingold EA, Grouse LH . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . etal. free .
• Vassilatis DK, Hohmann JG, Zeng H . The G protein-coupled receptor repertoires of human and mouse . Proc. Natl. Acad. Sci. U.S.A. . 100 . 8 . 4903–8 . 2003 . 12679517 . 10.1073/pnas.0230374100 . 153653 . 2003PNAS..100.4903V . etal. free .
• Gerhard DS, Wagner L, Feingold EA . The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 . etal.
• Parmigiani RB, Magalhães GS, Galante PA . A novel human G protein-coupled receptor is over-expressed in prostate cancer . Genet. Mol. Res. . 3 . 4 . 521–31 . 2005 . 15688318 . etal.
• Gloriam DE, Schiöth HB, Fredriksson R . Nine new human Rhodopsin family G-protein coupled receptors: identification, sequence characterisation and evolutionary relationship . Biochim. Biophys. Acta . 1722 . 3 . 235–46 . 2005 . 15777626 . 10.1016/j.bbagen.2004.12.001 .

Notes and References

1. Web site: Entrez Gene: GPR148 G protein-coupled receptor 148.