GNG12 explained

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 is a protein that in humans is encoded by the GNG12 gene.^{[1] [2]}

Further reading

• Morishita R, Nakayama H, Isobe T . Primary structure of a gamma subunit of G protein, gamma 12, and its phosphorylation by protein kinase C. . J. Biol. Chem. . 270 . 49 . 29469–75 . 1996 . 7493986 . 10.1074/jbc.270.49.29469 . etal. free .
• Maruyama K, Sugano S . Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. . Gene . 138 . 1–2 . 171–4 . 1994 . 8125298 . 10.1016/0378-1119(94)90802-8 .
• Morishita R, Saga S, Kawamura N . Differential localization of the gamma 3 and gamma 12 subunits of G proteins in the mammalian brain . J. Neurochem. . 68 . 2 . 820–7 . 1997 . 9003074 . 10.1046/j.1471-4159.1997.68020820.x . etal. free .
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K . Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library . Gene . 200 . 1–2 . 149–56 . 1997 . 9373149 . 10.1016/S0378-1119(97)00411-3 . etal.
• Asano T, Morishita R, Ueda H, Kato K . Selective association of G protein beta(4) with gamma(5) and gamma(12) subunits in bovine tissues . J. Biol. Chem. . 274 . 30 . 21425–9 . 1999 . 10409705 . 10.1074/jbc.274.30.21425 . free .
• Hu RM, Han ZG, Song HD . Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning . Proc. Natl. Acad. Sci. U.S.A. . 97 . 17 . 9543–8 . 2000 . 10931946 . 10.1073/pnas.160270997 . 16901 . 2000PNAS...97.9543H . etal. free .
• Cook LA, Schey KL, Cleator JH . Identification of a region in G protein gamma subunits conserved across species but hypervariable among subunit isoforms . Protein Sci. . 10 . 12 . 2548–55 . 2002 . 11714923 . 10.1110/ps.ps.26401 . 2374038 . etal.
• Strausberg RL, Feingold EA, Grouse LH . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . etal. free .
• Cuello F, Schulze RA, Heemeyer F . Activation of heterotrimeric G proteins by a high energy phosphate transfer via nucleoside diphosphate kinase (NDPK) B and Gbeta subunits. Complex formation of NDPK B with Gbeta gamma dimers and phosphorylation of His-266 IN Gbeta . J. Biol. Chem. . 278 . 9 . 7220–6 . 2003 . 12486123 . 10.1074/jbc.M210304200 . etal. free .
• Ota T, Suzuki Y, Nishikawa T . Complete sequencing and characterization of 21,243 full-length human cDNAs . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . etal. free .
• Bouwmeester T, Bauch A, Ruffner H . A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway . Nat. Cell Biol. . 6 . 2 . 97–105 . 2004 . 14743216 . 10.1038/ncb1086 . 11683986 . etal.
• Kato C, Mizutani T, Tamaki H . Characterization of heterotrimeric G protein complexes in rice plasma membrane . Plant J. . 38 . 2 . 320–31 . 2004 . 15078334 . 10.1111/j.1365-313X.2004.02046.x . etal. free .
• Suzuki Y, Yamashita R, Shirota M . Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions . Genome Res. . 14 . 9 . 1711–8 . 2004 . 15342556 . 10.1101/gr.2435604 . 515316 . etal.
• Gerhard DS, Wagner L, Feingold EA . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 . etal.
• Olsen JV, Blagoev B, Gnad F . Global, in vivo, and site-specific phosphorylation dynamics in signaling networks . Cell . 127 . 3 . 635–48 . 2006 . 17081983 . 10.1016/j.cell.2006.09.026 . 7827573 . etal. free .

Notes and References

1. Hurowitz EH, Melnyk JM, Chen YJ, Kouros-Mehr H, Simon MI, Shizuya H . Genomic characterization of the human heterotrimeric G protein alpha, beta, and gamma subunit genes . DNA Res . 7 . 2 . 111–20 . Sep 2000 . 10819326 . 10.1093/dnares/7.2.111 . free .
2. Web site: Entrez Gene: GNG12 guanine nucleotide binding protein (G protein), gamma 12.