SLC2A4RG explained

SLC2A4 regulator is a protein that in humans is encoded by the SLC2A4RG gene.^{[1] [2]}

The protein encoded by this gene is a nuclear transcription factor involved in the activation of the solute carrier family 2 member 4 gene. The encoded protein interacts with another transcription factor, myocyte enhancer factor 2, to activate transcription of this gene.

Further reading

• Bonaldo MF, Lennon G, Soares MB . Normalization and subtraction: two approaches to facilitate gene discovery . Genome Res. . 6 . 9 . 791–806 . 1997 . 8889548 . 10.1101/gr.6.9.791 . free .
• Xu XR, Huang J, Xu ZG, etal . Insight into hepatocellular carcinogenesis at transcriptome level by comparing gene expression profiles of hepatocellular carcinoma with those of corresponding noncancerous liver . Proc. Natl. Acad. Sci. U.S.A. . 98 . 26 . 15089–94 . 2002 . 11752456 . 10.1073/pnas.241522398 . 64988 . 2001PNAS...9815089X . free .
• Deloukas P, Matthews LH, Ashurst J, etal . The DNA sequence and comparative analysis of human chromosome 20 . Nature . 414 . 6866 . 865–71 . 2002 . 11780052 . 10.1038/414865a . 2001Natur.414..865D . free .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Tanaka K, Shouguchi-Miyata J, Miyamoto N, Ikeda JE . Novel nuclear shuttle proteins, HDBP1 and HDBP2, bind to neuronal cell-specific cis-regulatory element in the promoter for the human Huntington's disease gene . J. Biol. Chem. . 279 . 8 . 7275–86 . 2004 . 14625278 . 10.1074/jbc.M310726200 . free .
• Knight JB, Eyster CA, Griesel BA, Olson AL . Regulation of the human GLUT4 gene promoter: interaction between a transcriptional activator and myocyte enhancer factor 2A . Proc. Natl. Acad. Sci. U.S.A. . 100 . 25 . 14725–30 . 2004 . 14630949 . 10.1073/pnas.2432756100 . 299781 . free .
• Gerhard DS, Wagner L, Feingold EA, etal . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
• McGee SL, Sparling D, Olson AL, Hargreaves M . Exercise increases MEF2- and GEF DNA-binding activity in human skeletal muscle . FASEB J. . 20 . 2 . 348–9 . 2006 . 16368714 . 10.1096/fj.05-4671fje . free . 13881696 .

Notes and References

1. Oshel KM, Knight JB, Cao KT, Thai MV, Olson AL . Identification of a 30-base pair regulatory element and novel DNA binding protein that regulates the human GLUT4 promoter in transgenic mice . J Biol Chem . 275 . 31 . 23666–73 . Sep 2000 . 10825161 . 10.1074/jbc.M001452200 . free .
2. Web site: Entrez Gene: SLC2A4RG SLC2A4 regulator.