GISSI explained

The Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico (GISSI) (Italian group for the study of the survival of myocardial infarction) is a cardiology research group founded as a collaboration between two Italian organisations – the Mario Negri Institute for Pharmacological Research and the Associazione Nazionale dei Medici Cardiologi Ospedalieri (ANMCO).^{[1] [2]}

Four large-scale clinical trials (GISSI 1,^[3] GISSI 2,^[3] GISSI 3,^[4] GISSI Prevention) have involved over 60,000 people with acute myocardial infarction (AMI).^{[1] [5] [6]}

Selected publications

• Effectiveness of intravenous thrombolytic treatment in acute myocardial infarction. Gruppo Italiano per lo Studio della Streptochinasi nell'Infarto Miocardico (GISSI) . Lancet . 1 . 8478 . 397–402 . 1986 . 2868337 . 10.1016/s0140-6736(86)92368-8. 54241689 .
• Long-term effects of intravenous thrombolysis in acute myocardial infarction: final report of the GISSI study. Gruppo Italiano per lo Studio della Streptochi-nasi nell'Infarto Miocardico (GISSI) . Lancet . 2 . 8564 . 871–4 . 1987 . 2889079 . 10.1016/s0140-6736(87)91369-9.
• GISSI-2: a factorial randomised trial of alteplase versus streptokinase and heparin versus no heparin among 12,490 patients with acute myocardial infarction. Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico . Lancet . 336 . 8707 . 65–71 . 1990 . 1975321 . 10.1016/0140-6736(90)91589-3. 54431361 .
• The international study group. In-hospital mortality and clinical course of 20,891 patients with suspected acute myocardial infarction randomised between alteplase and streptokinase with or without heparin. The International Study Group . Lancet . 336 . 8707 . 71–5 . 1990 . 1975322 . 10.1016/0140-6736(90)91590-7. 6756599 .
• GISSI-3: effects of lisinopril and transdermal glyceryl trinitrate singly and together on 6-week mortality and ventricular function after acute myocardial infarction. Gruppo Italiano per lo Studio della Sopravvivenza nell'infarto Miocardico . Lancet . 343 . 8906 . 1115–22 . 1994 . 7910229 . 10.1016/s0140-6736(94)90232-1. 54310582 .
• Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico . Lancet . 354 . 9177 . 447–55 . 1999 . 10465168 . 10.1016/S0140-6736(99)07072-5. 2649173 .

External links

• Gissi website

Notes and References

1. Web site: GISSI. www.gissi.org. 12 April 2020.
2. Book: Tools For Evaluating Health Technologies: 5 Background Papers. 2004. DIANE Publishing. 978-0-7881-1832-6. 83. en.
3. Maggioni. Aldo P.. Franzosi. Maria G.. Fresco. Claudio. Turazza. Fabio. Tognoni. Gianni. 1990-04-01. GISSI Trials in Acute Myocardial Infarction: Rationale, Design, and Results. Chest. en. 97. 4. 146S–150S. 10.1378/chest.97.4_Supplement.146S. 2182307. 0012-3692.
4. Book: Aronow. Wilbert. Cardiovascular Disease In The Elderly, Third Edition, Revised And Expanded. Fleg. Jerome L.. Aronow. Wilbert S.. Rich. Michael W.. 2004. CRC Press. 978-0-8247-5095-4. en. 357.
5. Book: Myat. Aung. Landmark Papers in Cardiovascular Medicine. Gershlick. A. H.. Gershlick. Tony. 2012. Oxford University Press. 978-0-19-959476-4. 38–39. en.
6. Book: Maisch. Bernhard. Cardiovascular Benefits of Omega-3 Polyunsaturated Fatty Acids. Oelze. R.. 2006. IOS Press. 978-1-58603-707-9. 82. en.