GINS1 explained

DNA replication complex GINS protein PSF1 is a protein that in humans is encoded by the GINS1 gene.^{[1] [2] [3]}

See also

• GINS (protein complex)
• Eukaryotic DNA replication#GINS Explains role of GINS during DNA replication in eukaryotic cells.

Further reading

• Kamada K, Kubota Y, Arata T . Structure of the human GINS complex and its assembly and functional interface in replication initiation. . Nat. Struct. Mol. Biol. . 14 . 5 . 388–96 . 2007 . 17417653 . 10.1038/nsmb1231 . 23124923 . etal.
• Hayashi R, Arauchi T, Tategu M . A combined computational and experimental study on the structure-regulation relationships of putative mammalian DNA replication initiator GINS. . Genomics Proteomics Bioinformatics . 4 . 3 . 156–64 . 2007 . 17127213 . 10.1016/S1672-0229(06)60028-4 . etal. 5054078 .
• Ueno M, Itoh M, Kong L . PSF1 is essential for early embryogenesis in mice. . Mol. Cell. Biol. . 25 . 23 . 10528–32 . 2005 . 16287864 . 10.1128/MCB.25.23.10528-10532.2005 . 1291228 . etal.
• Gerhard DS, Wagner L, Feingold EA . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 . etal.
• Strausberg RL, Feingold EA, Grouse LH . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . etal. free .
• Deloukas P, Matthews LH, Ashurst J . The DNA sequence and comparative analysis of human chromosome 20. . Nature . 414 . 6866 . 865–71 . 2002 . 11780052 . 10.1038/414865a . 2001Natur.414..865D . etal. free .
• Hoja MR, Wahlestedt C, Höög C . A visual intracellular classification strategy for uncharacterized human proteins. . Exp. Cell Res. . 259 . 1 . 239–46 . 2000 . 10942595 . 10.1006/excr.2000.4948 .

Notes and References

1. Nagase T, Seki N, Ishikawa K, Tanaka A, Nomura N . Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1 . DNA Res . 3 . 1 . 17–24 . Nov 1996 . 8724849 . 10.1093/dnares/3.1.17 . free .
2. Chiang PW, Wang S, Smithivas P, Song WJ, Ramamoorthy S, Hillman J, Puett S, Van Keuren ML, Crombez E, Kumar A, Glover TW, Miller DE, Tsai CH, Blackburn CC, Chen XN, Sun Z, Cheng JF, Korenberg JR, Kurnit DM . Identification and analysis of the human and murine putative chromatin structure regulator SUPT6H and Supt6h . Genomics . 34 . 3 . 328–33 . Sep 1996 . 8786132 . 10.1006/geno.1996.0294 .
3. Web site: Entrez Gene: GINS1 GINS complex subunit 1 (Psf1 homolog).