GDP-D-glucose phosphorylase explained

GDP-D-glucose phosphorylase
Ec Number:	2.7.7.78

GDP-D-glucose phosphorylase is an enzyme with systematic name GDP:alpha-D-glucose 1-phosphate guanylyltransferase.^[1] This enzyme catalyses the following chemical reaction

\rightleftharpoons alpha-D-glucose 1-phosphate + GDP

The enzyme may be involved in prevention of misincorporation of glucose in place of mannose residues into glycoconjugates.

Notes and References

1. Adler LN, Gomez TA, Clarke SG, Linster CL . A novel GDP-D-glucose phosphorylase involved in quality control of the nucleoside diphosphate sugar pool in Caenorhabditis elegans and mammals . The Journal of Biological Chemistry . 286 . 24 . 21511–23 . June 2011 . 21507950 . 3122210 . 10.1074/jbc.m111.238774 . free .