GCN1L1 explained
Translational activator GCN1 is a protein that in humans is encoded by the GCN1L1 gene.[1] [2]
Interactions
GCN1L1 has been shown to interact with CDC5L.[3]
Further reading
- Nakajima D, Okazaki N, Yamakawa H . Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. . DNA Res. . 9 . 3 . 99–106 . 2003 . 12168954 . 10.1093/dnares/9.3.99 . etal. free .
- Nagase T, Seki N, Ishikawa K . Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. . DNA Res. . 3 . 5 . 321–9, 341–54 . 1997 . 9039502 . 10.1093/dnares/3.5.321 . etal. free .
- Andersen JS, Lyon CE, Fox AH . Directed proteomic analysis of the human nucleolus. . Curr. Biol. . 12 . 1 . 1–11 . 2002 . 11790298 . 10.1016/S0960-9822(01)00650-9 . 14132033 . etal. free . 2002CBio...12....1A .
- Strausberg RL, Feingold EA, Grouse LH . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . etal. 2002PNAS...9916899M . free .
- Bouwmeester T, Bauch A, Ruffner H . A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. . Nat. Cell Biol. . 6 . 2 . 97–105 . 2004 . 14743216 . 10.1038/ncb1086 . 11683986 . etal.
- Gerhard DS, Wagner L, Feingold EA . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 . etal.
- Andersen JS, Lam YW, Leung AK . Nucleolar proteome dynamics. . Nature . 433 . 7021 . 77–83 . 2005 . 15635413 . 10.1038/nature03207 . etal. 2005Natur.433...77A . 4344740 .
- Scherer SE, Muzny DM, Buhay CJ . The finished DNA sequence of human chromosome 12. . Nature . 440 . 7082 . 346–51 . 2006 . 16541075 . 10.1038/nature04569 . etal. 2006Natur.440..346S . free .
- Ewing RM, Chu P, Elisma F . Large-scale mapping of human protein-protein interactions by mass spectrometry. . Mol. Syst. Biol. . 3 . 1. 89 . 2007 . 17353931 . 10.1038/msb4100134 . 1847948 . etal.
Notes and References
- Marton MJ, Vazquez de Aldana CR, Qiu H, Chakraburtty K, Hinnebusch AG . Evidence that GCN1 and GCN20, translational regulators of GCN4, function on elongating ribosomes in activation of eIF2alpha kinase GCN2 . Mol Cell Biol . 17 . 8 . 4474–89 . August 1997 . 9234705 . 232301 . 10.1128/mcb.17.8.4474.
- Web site: Entrez Gene: GCN1L1 GCN1 general control of amino-acid synthesis 1-like 1 (yeast).
- Ajuh . P . Kuster B . Panov K . Zomerdijk J C . Mann M . Lamond A I . December 2000 . Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry . EMBO J. . 19 . 23 . 6569–81 . ENGLAND. 0261-4189. 11101529 . 10.1093/emboj/19.23.6569 . 305846 .
