GAT100 explained

GAT100 is a negative allosteric modulator of the cannabinoid CB₁ receptor.^{[1] [2]}

See also

• Org 27569
• PSNCBAM-1
• ZCZ-011

References

1. Kulkarni PM, Kulkarni AR, Korde A, Tichkule RB, Laprairie RB, Denovan-Wright EM, Zhou H, Janero DR, Zvonok N, Makriyannis A, Cascio MG, Pertwee RG, Thakur GA . 6 . Novel Electrophilic and Photoaffinity Covalent Probes for Mapping the Cannabinoid 1 Receptor Allosteric Site(s) . Journal of Medicinal Chemistry . 59 . 1 . 44–60 . January 2016 . 26529344 . 4716578 . 10.1021/acs.jmedchem.5b01303 . Alexandros Makriyannis .
2. Laprairie RB, Kulkarni AR, Kulkarni PM, Hurst DP, Lynch D, Reggio PH, Janero DR, Pertwee RG, Stevenson LA, Kelly ME, Denovan-Wright EM, Thakur GA . 6 . Mapping Cannabinoid 1 Receptor Allosteric Site(s): Critical Molecular Determinant and Signaling Profile of GAT100, a Novel, Potent, and Irreversibly Binding Probe . ACS Chemical Neuroscience . 7 . 6 . 776–98 . June 2016 . 27046127 . 5358098 . 10.1021/acschemneuro.6b00041 .