GABRR3 explained

Gamma-aminobutyric acid receptor subunit rho-3 is a protein that in humans is encoded by the GABRR3 gene.^[1] The protein encoded by this gene is a subunit of the GABA_A-ρ receptor.

Further reading

• Croci C, Brändstatter JH, Enz R . ZIP3, a new splice variant of the PKC-zeta-interacting protein family, binds to GABAC receptors, PKC-zeta, and Kv beta 2 . J. Biol. Chem. . 278 . 8 . 6128–6135 . 2003 . 12431995 . 10.1074/jbc.M205162200 . free .
• Craddock N, Jones L, Jones IR . Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype . Mol. Psychiatry . 15 . 2 . 146–153 . 2010 . 19078961 . 10.1038/mp.2008.66 . etal . 3967096.
• Alakuijala A, Palgi M, Wegelius K . GABA receptor rho subunit expression in the developing rat brain . Brain Res. Dev. Brain Res. . 154 . 1 . 15–23 . 2005 . 15617751 . 10.1016/j.devbrainres.2004.09.010 . etal.
• Bailey ME, Albrecht BE, Johnson KJ, Darlison MG . Genetic linkage and radiation hybrid mapping of the three human GABA(C) receptor rho subunit genes: GABRR1, GABRR2 and GABRR3 . Biochim. Biophys. Acta . 1447 . 2–3 . 307–312 . 1999 . 10542332 . 10.1016/S0167-4781(99)00167-0.
• Gratacòs M, Costas J, de Cid R . Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment . Am. J. Med. Genet. B Neuropsychiatr. Genet. . 150B . 6 . 808–816 . 2009 . 19086053 . 10.1002/ajmg.b.30902 . 44524739 . etal. free .
• Muzny DM, Scherer SE, Kaul R . The DNA sequence, annotation and analysis of human chromosome 3 . Nature . 440 . 7088 . 1194–1198 . 2006 . 16641997 . 10.1038/nature04728 . 2006Natur.440.1194M . etal. free .

Notes and References

1. Bailey ME, Albrecht BE, Johnson KJ, Darlison MG . Genetic linkage and radiation hybrid mapping of the three human GABA(C) receptor rho subunit genes: GABRR1, GABRR2 and GABRR3 . Biochim. Biophys. Acta . 1447 . 2–3 . 307–312 . October 1999 . 10542332 . 10.1016/S0167-4781(99)00167-0 .