GABARAPL2 explained

Gamma-aminobutyric acid receptor-associated protein-like 2 is a protein that in humans is encoded by the GABARAPL2 gene.^{[1] [2]}

Interactions

GABARAPL2 has been shown to interact with ULK1,^[3] ATG4B,^{[4] [5]} and FAM134B.^[6]

Further reading

• Rohwer A, Kittstein W, Marks F, Gschwendt M . Cloning, expression and characterization of an A6-related protein . European Journal of Biochemistry . 263 . 2 . 518–25 . Jul 1999 . 10406962 . 10.1046/j.1432-1327.1999.00537.x . free .
• Sagiv Y, Legesse-Miller A, Porat A, Elazar Z . GATE-16, a membrane transport modulator, interacts with NSF and the Golgi v-SNARE GOS-28 . The EMBO Journal . 19 . 7 . 1494–504 . Apr 2000 . 10747018 . 310219 . 10.1093/emboj/19.7.1494 .
• Hartley JL, Temple GF, Brasch MA . DNA cloning using in vitro site-specific recombination . Genome Research . 10 . 11 . 1788–95 . Nov 2000 . 11076863 . 310948 . 10.1101/gr.143000 .
• Okazaki N, Yan J, Yuasa S, Ueno T, Kominami E, Masuho Y, Koga H, Muramatsu M . Interaction of the Unc-51-like kinase and microtubule-associated protein light chain 3 related proteins in the brain: possible role of vesicular transport in axonal elongation . Brain Research. Molecular Brain Research . 85 . 1–2 . 1–12 . Dec 2000 . 11146101 . 10.1016/S0169-328X(00)00218-7 .
• Simpson JC, Wellenreuther R, Poustka A, Pepperkok R, Wiemann S . Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing . EMBO Reports . 1 . 3 . 287–92 . Sep 2000 . 11256614 . 1083732 . 10.1093/embo-reports/kvd058 .
• Tanida I, Tanida-Miyake E, Nishitani T, Komatsu M, Yamazaki H, Ueno T, Kominami E . Murine Apg12p has a substrate preference for murine Apg7p over three Apg8p homologs . Biochemical and Biophysical Research Communications . 292 . 1 . 256–62 . Mar 2002 . 11890701 . 10.1006/bbrc.2002.6645 .
• Scherz-Shouval R, Sagiv Y, Shorer H, Elazar Z . The COOH terminus of GATE-16, an intra-Golgi transport modulator, is cleaved by the human cysteine protease HsApg4A . The Journal of Biological Chemistry . 278 . 16 . 14053–8 . Apr 2003 . 12473658 . 10.1074/jbc.M212108200 . free .
• Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sültmann H, Poustka A . From ORFeome to biology: a functional genomics pipeline . Genome Research . 14 . 10B . 2136–44 . Oct 2004 . 15489336 . 528930 . 10.1101/gr.2576704 .
• Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M . Towards a proteome-scale map of the human protein-protein interaction network . Nature . 437 . 7062 . 1173–8 . Oct 2005 . 16189514 . 10.1038/nature04209 . 2005Natur.437.1173R . 4427026 .
• Sou YS, Tanida I, Komatsu M, Ueno T, Kominami E . Phosphatidylserine in addition to phosphatidylethanolamine is an in vitro target of the mammalian Atg8 modifiers, LC3, GABARAP, and GATE-16 . The Journal of Biological Chemistry . 281 . 6 . 3017–24 . Feb 2006 . 16303767 . 10.1074/jbc.M505888200 . free .
• Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S . The LIFEdb database in 2006 . Nucleic Acids Research . 34 . Database issue . D415-8 . Jan 2006 . 16381901 . 1347501 . 10.1093/nar/gkj139 .
• Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D . Large-scale mapping of human protein-protein interactions by mass spectrometry . Molecular Systems Biology . 3 . 1 . 89 . 2007 . 17353931 . 1847948 . 10.1038/msb4100134 .

Notes and References

1. Xin Y, Yu L, Chen Z, Zheng L, Fu Q, Jiang J, Zhang P, Gong R, Zhao S . Cloning, expression patterns, and chromosome localization of three human and two mouse homologues of GABA(A) receptor-associated protein . Genomics . 74 . 3 . 408–13 . Jun 2001 . 11414770 . 10.1006/geno.2001.6555 .
2. Web site: Entrez Gene: GABARAPL2 GABA(A) receptor-associated protein-like 2.
3. Okazaki N, Yan J, Yuasa S, Ueno T, Kominami E, Masuho Y, Koga H, Muramatsu M . Interaction of the Unc-51-like kinase and microtubule-associated protein light chain 3 related proteins in the brain: possible role of vesicular transport in axonal elongation . Brain Research. Molecular Brain Research . 85 . 1–2 . 1–12 . Dec 2000 . 11146101 . 10.1016/S0169-328X(00)00218-7 .
4. Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D . Large-scale mapping of human protein-protein interactions by mass spectrometry . Molecular Systems Biology . 3 . 1 . 89 . 2007 . 17353931 . 1847948 . 10.1038/msb4100134 .
5. Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, Stroedicke M, Zenkner M, Schoenherr A, Koeppen S, Timm J, Mintzlaff S, Abraham C, Bock N, Kietzmann S, Goedde A, Toksöz E, Droege A, Krobitsch S, Korn B, Birchmeier W, Lehrach H, Wanker EE . A human protein-protein interaction network: a resource for annotating the proteome . Cell . 122 . 6 . 957–68 . Sep 2005 . 16169070 . 10.1016/j.cell.2005.08.029 . 11858/00-001M-0000-0010-8592-0 . 8235923 . free .
6. Khaminets. Aliaksandr. Heinrich. Theresa. Mari. Muriel. Grumati. Paolo. Huebner. Antje K.. Akutsu. Masato. Liebmann. Lutz. Stolz. Alexandra. Nietzsche. Sandor. 2015-06-18. Regulation of endoplasmic reticulum turnover by selective autophagy. Nature. en. 522. 7556. 354–358. 10.1038/nature14498. 26040720. 2015Natur.522..354K. 4449106. 0028-0836.