G3BP2 explained

Ras GTPase-activating protein-binding protein 2 is an enzyme that in humans is encoded by the G3BP2 gene.^{[1] [2] [3]}

Interactions

G3BP2 has been shown to interact with IκBα.^[4]

Further reading

• Kim MM, Wiederschain D, Kennedy D, Hansen E, Yuan ZM . Modulation of p53 and MDM2 activity by novel interaction with Ras-GAP binding proteins (G3BP) . Oncogene . 26 . 29 . 4209–15 . June 2007 . 17297477 . 10.1038/sj.onc.1210212 . 20028334 .
• Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M . Global, in vivo, and site-specific phosphorylation dynamics in signaling networks . Cell . 127 . 3 . 635–48 . November 2006 . 17081983 . 10.1016/j.cell.2006.09.026 . 7827573 . free .
• Ong SE, Mittler G, Mann M . Identifying and quantifying in vivo methylation sites by heavy methyl SILAC . Nature Methods . 1 . 2 . 119–26 . November 2004 . 15782174 . 10.1038/nmeth715 . 6654604 .
• Ballif BA, Villén J, Beausoleil SA, Schwartz D, Gygi SP . Phosphoproteomic analysis of the developing mouse brain . Molecular & Cellular Proteomics . 3 . 11 . 1093–101 . November 2004 . 15345747 . 10.1074/mcp.M400085-MCP200 . free .
• Prigent M, Barlat I, Langen H, Dargemont C . IkappaBalpha and IkappaBalpha /NF-kappa B complexes are retained in the cytoplasm through interaction with a novel partner, RasGAP SH3-binding protein 2 . The Journal of Biological Chemistry . 275 . 46 . 36441–9 . November 2000 . 10969074 . 10.1074/jbc.M004751200 . free .
• Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA . 6 . Large-scale concatenation cDNA sequencing . Genome Research . 7 . 4 . 353–8 . April 1997 . 9110174 . 139146 . 10.1101/gr.7.4.353 .
• Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA . A "double adaptor" method for improved shotgun library construction . Analytical Biochemistry . 236 . 1 . 107–13 . April 1996 . 8619474 . 10.1006/abio.1996.0138 .

Notes and References

1. Ishikawa K, Nagase T, Suyama M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O . 6 . Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro . DNA Research . 5 . 3 . 169–76 . June 1998 . 9734811 . 10.1093/dnares/5.3.169 . free .
2. Kennedy D, Wood SA, Ramsdale T, Tam PP, Steiner KA, Mattick JS . Identification of a mouse orthologue of the human ras-GAP-SH3-domain binding protein and structural confirmation that these proteins contain an RNA recognition motif . Biomedical Peptides, Proteins & Nucleic Acids . 2 . 3 . 93–9 . June 1998 . 9575347 .
3. Web site: Entrez Gene: G3BP2 GTPase activating protein (SH3 domain) binding protein 2.
4. Prigent M, Barlat I, Langen H, Dargemont C . IkappaBalpha and IkappaBalpha /NF-kappa B complexes are retained in the cytoplasm through interaction with a novel partner, RasGAP SH3-binding protein 2 . The Journal of Biological Chemistry . 275 . 46 . 36441–9 . November 2000 . 10969074 . 10.1074/jbc.M004751200 . free .