Friedrich Loeffler Explained

Friedrich August Johannes Loeffler
Birth Date:	24 June 1852
Birth Place:	Frankfurt (Oder)
Death Date:	9 April 1915 (aged 62)
Death Place:	Berlin
Nationality:	German
Field:	Bacteriology
Work Institutions:	University of Greifswald Friedrich Loeffler Institute
Alma Mater:	University of Würzburg University of Berlin
Known For:	Corynebacterium diphtheriae Aphthovirus

Friedrich August Johannes Loeffler (pronounced as /de/; 24 June 18529 April 1915) was a German bacteriologist at the University of Greifswald.

Biography

He obtained his M.D. degree from the University of Berlin in 1874. He worked with Robert Koch from 1879 to 1884^[1] as an assistant in the Imperial Health Office in Berlin. In 1884, he became staff physician at the Friedrich Wilhelm Institute in Berlin, and four years later became professor at the University of Greifswald.^[2]

His development of original methods of staining rendered an important and lasting service to bacteriology.^[2] Early in his career, he began a study of parasitic diseases.^[3] Among his discoveries was the organism causing diphtheria (Corynebacterium diphtheriae) and the cause of foot-and-mouth disease (Aphthovirus). His description of the diphtheria bacillus, published in 1884, was the originating cause of an antitoxin treatment.^[3] He also created Löffler's serum, a coagulated blood serum used for the detection of the bacteria. In 1887, he founded the Centralblatt für Bakteriologie und Parasitenkunde.^{[2] [4]}

The Friedrich Loeffler Institute on the Isle of Riems near Greifswald, as well as the Friedrich Loeffler Institute of Medical Microbiology at the Greifswald Medical School of the University of Greifswald, have been named in his honor.

Selected publications

• with Robert Koch and Georg Theodor August Gaffky: Ueber die Verwerthbarkeit heißer Wasserdämpfe zu Desinfectionszwecken. (On the effectiveness of hot water vapors for purposes of disinfection) In: Mitteilungen aus dem Kaiserlichen Gesundheitsamte. 1, 1881, pp. 322–340.
• Vorlesungen über die geschichtliche Entwicklung der Lehre von den Bakterien. (Lectures on the historical development of the theory of bacteria) Leipzig 1887.
• with Paul Frosch: Summarische Bericht über die Ergebnisse der Untersuchungen der Kommission zur Erforschung der Maul- und Klauenseuche bei dem Institut für Infektionskrankheiten in Berlin. (Summary report on the results of the investigations by the Commission for Research into Foot and Mouth Disease at the Institute for Infectious Diseases in Berlin) In: Centralblatt für Bakteriologie und Parasitenkunde. volume 22, 1897, pp. 257–259 (part 1), and volume 23, 1898, pp. 371–391 (part 2).
• Zur Immunitätsfrage. (On the question of immunity) In: Mitteilungen aus dem Kaiserlichen Gesundheitsamte. 1, 1882, pp. 134–187.
• Untersuchungen über die Bedeutung der Mikroorganismen für die Entstehung der Diphtherie beim Menschen, bei der Taube und beim Kalbe. (Investigations into the importance of microorganisms for the development of diphtheria in humans, pigeons and calves) In: Mitteilungen aus dem Kaiserlichen Gesundheitsamte. 2, 1884, pp. 421–499.

References

• 13632391. Bochalli R. January 1959. 13. 1. Medizinische Monatsschrift. 59–62. Friedrich Loeffler, his life & works; on the occasion of 75th return of the anniversary of the discovery of the diphtheria bacillus..
• 13955107. Howard DH. July 1963. Friedrich LOEFFLER and the Thessalian field mouse plague of 1892.. 18. 3. Jornal de historia da medicina. 272–81. 10.1093/jhmas/xviii.3.272.
• 5327173. Kaiser G. 1965. Friedrich Loeffler on his 80th birthday. 58. 2. Archiv für orthopädische und Unfall-Chirurgie. 85–7. 10.1007/BF00416118. Friedrich Loeffler zum 80. Geburtstag. 28053507.
• 4875506. Matiner HR. 1967. In memory of Friedrich Loeffler. 62. 4. Archiv für orthopädische und Unfall-Chirurgie. 269–72. 10.1007/BF00416209. Nachruf für Friedrich Loeffler. 41107594. free.
• 4233465. Blencke B. August 1967. 103. 3. Zeitschrift für Orthopädie und ihre Grenzgebiete. 273–6. In memory of Professor Friedrich Loeffler.
• 4898725. 10 November 1969. Friedrich Loeffler (1852–1915). Klebs-Loeffler bacillus. 210. 6. JAMA. 1096–7. 10.1001/jama.210.6.1096.
• 29591. Hauck P. 1978. 32. 3. Archiv für experimentelle Veterinärmedizin. 311–2. Opening address of the scientific festive colloquium commemorating the 125th birthday of Friedrich Loeffler on June 21st and 22d, 1977 in Greifswald.
• 358941. Hüller H, Berndt HG, Dittrich M . 1978. 32. 3. Archiv für experimentelle Veterinärmedizin. 313–8. The work of Friedrich Loeffler in Greifswald.
• 6349609. Bethge R, Knöfler EW . May 1983. 30. 5. Beiträge zur Orthopädie und Traumatologie. 233–6. 30 years of the East Germany Orthopedic Society—in memory of its co-founder and 1st chairman Friedrich Loeffler.
• 3907574. Beer J. September 1985. 39. 5. Archiv für experimentelle Veterinärmedizin. 623–30. Friedrich Loeffler as a founder of virology.
• 2198709. Mochmann H, Köhler W . 1990. 84. 8. Zeitschrift für ärztliche Fortbildung. 400–6. Friedrich Loeffler (1852–1915)--his contributions to bacteriology and virology. In memory of the 75th anniversary of his death.
• 12506922. Wittmann W, Lafer EM . 2002. Friedrich Loeffler's way to the Isle of Riems near Greifswald. 27. 1–4. Historia medicinae veterinariae. 217–30.

External links

• www.fli.bund.deGerman Federal Research Institute for Animal Health

Notes and References

1. [Isaac Asimov]
2. Loeffler, Friedrich.
3. Löffler, Friedrich.
4. Book: Centralblatt für Bakteriologie und Parasitenkunde. 1887. Jena. Verlag von Gustav Fischer.