Friedrich Gaedcke Explained

Friedrich Gaedcke
Birth Date:5 June 1828
Nationality:German
Field:pharmaceutics
Known For:discovering cocaine

Friedrich Georg Carl (Friedrich) Gaedcke (5 June 1828 – 19 September 1890) was a German chemist.[1] He was the first person to isolate the cocaine alkaloid in 1855.[2] [3]

Life

Gaedcke worked in a pharmacy in Rostock and studied in Rostock between 1850 and 1851. In 1856, he took over a pharmacy in Dömitz which he ran for 34 years. He is described as having made contributions to the pharmaceutical history of Mecklenburg[1]

Discovery of Cocaine

Working with coca leaves, Gaedcke isolated the cocaine molecule.[3] Gaedcke named the alkaloid “erythroxyline,” and published a description in the journal Archiv der Pharmazie in 1855.[4] [5] He described the alkaloid as being of small crystal molecules with needle-like points on four to six sides.[3] He reported the numbing effects of the molecule on himself following a small tongue test.[3] Gaedcke's research received little attention at the time of its publication but would come to prominence a few years later following further work by Albert Niemann and scientists.[3] He is believed to have carried out his research in the private laboratory of Franz Leopold Sonnenschein.[6]

Notes and References

  1. Web site: [Early history of cocaine isolation: Domitzer pharmacist Friedrich Gaedcke (1828-1890); contribution to Mecklenburg pharmaceutical history] ]. PubMed . 30 June 2024.
  2. Book: Luch, Andreas . Molecular, Clinical and Environmental Toxicology . Springer Science & Business Media . Basel Boston . 2009-04-03 . 978-3-7643-8336-7 . 20.
  3. Book: West, Krista . Cocaine and Crack . Infobase Publishing . 2008 . 978-1-4381-1822-2 . 47.
  4. Ueber das Erythroxylin, dargestellt aus den Blättern des in Südamerika cultivirten Strauches Erythroxylon Coca Lam . F. Gaedcke . Archiv der Pharmazie . 132 . 2 . 141–150 . 1855 . 10.1002/ardp.18551320208 . 86030231 .
  5. Early history of cocaine isolation: Domitzer pharmacist Friedrich Gaedcke (1828–1890); contribution to Mecklenburg pharmaceutical history . Zaunick R. . Beitr Gesch Pharm Ihrer Nachbargeb. . 7 . 2 . 5–15 . 1956 . 13395966.
  6. Anesthesia History Association Newsletter, Volumes 1–13, Issue 2. 1982, page 4