She took part in the Battle of Minorca (1756) and in the Battle of Lagos. She was part of Bougainville's squadron for the Naval operations in the American Revolutionary War, and took part in the operations before the Battle of Rhode Island, in the Battle of Grenada, and in the siege of Savannah.
In July 1781, she took part in the Invasion of Minorca. On 9 August, she captured the 700-tonne HMS Scarborough.
By the time of the invasion of Egypt, Guerrier should have been decommissioned for two years,[1] but was nevertheless incorporated in the invasion fleet. She took part in the Battle of the Nile, where she was captured by the British. She was so badly damaged that she was burnt.