| Season: | 2000–01 |
| Nextseason: | 2001–02 |
The Division 2 season 2000/2001, organised by the LNF was won by FC Sochaux-Montbéliard and saw the promotions of FC Sochaux-Montbéliard, FC Lorient and Montpellier HSC, whereas AS Cannes and Angers SCO were relegated to National.
| Rank | Player | Club | Goals |
|---|---|---|---|
| 1 |  Francileudo Santos | Sochaux | 21 |
| 2 |  Alain Caveglia | Le Havre | 16 |
| 3 |  Élie Kroupi | Lorient | 15 |
| 4 | Laurent Dufresne | Châteauroux | 14 |
| 5 | Cyrille Watier | Caen | 13 |
| David Suarez | Cannes | ||
| Lilian Compan | Créteil | ||
| Toifilou Maoulida | Montpellier | ||
| 9 | Réginald Ray | Beauvais | 12 |
| Lionel Rouxel | Laval | ||
| Pierre-Alain Frau | Sochaux |