| Princess Friederike | |
| Duchess of Mecklenburg-Strelitz | |
| House: | Hesse-Darmstadt |
| Full Name: | Friederike Caroline Luise |
| Father: | Prince George William of Hesse-Darmstadt |
| Mother: | Countess Maria Louise Albertine of Leiningen-Falkenburg-Dagsburg |
| Birth Date: | 20 August 1752 |
| Birth Place: | Darmstadt, Landgraviate of Hesse-Darmstadt, Holy Roman Empire |
| Death Place: | Hanover, Electorate of Brunswick-Lüneburg, Holy Roman Empire |
Princess Friederike Caroline Luise of Hesse-Darmstadt (20 August 1752 - 22 May 1782) was a member of the House of Hesse and by marriage a Duchess of Mecklenburg-Strelitz.
Friederike was born in Darmstadt, the eldest daughter of Prince George William of Hesse-Darmstadt, second son of Louis VIII, Landgrave of Hesse-Darmstadt, and his wife, Countess Maria Louise Albertine of Leiningen-Falkenburg-Dagsburg.
Friederike married Duke Charles of Mecklenburg-Strelitz on 18 September 1768 in Darmstadt.[1] After her death, Charles married her younger sister Charlotte in 1784.
Friederike died in 1782 in Hanover (where Charles was field marshal of the household brigade), three days after giving birth to her tenth child, Augusta, who lived just one day. Friederike is buried in the royal crypt of the church of St. John the Baptist in Mirow.
Friederike and Charles had ten children between 1769 and 1782, six of whom survived to adulthood.
Friederike is the most recent common matrilineal ancestor of Harald V of Norway (via Louise), Henri, Grand Duke of Luxembourg (also via Louise), Willem-Alexander of the Netherlands (via Charlotte Georgine), and Frederik X of Denmark (via Frederica).