| František Šafránek | |
| Birth Date: | 1931 1, df=yes |
| Birth Place: | Prague, Czechoslovakia |
| Position: | Defender |
| Youthyears1: | 1939–1949 |
| Youthclubs1: | Sportovní sdružení Vršovice |
| Years1: | 1949–1952 |
| Clubs1: | Spartak Sokolovo |
| Years2: | 1952–1966 |
| Clubs2: | Dukla Prague |
| Years3: | 1966–1970 |
| Clubs3: | Spartak BS Vlašim |
| Years4: | 1974–1976 |
| Clubs4: | RH Strašnice |
| Nationalyears1: | 1951–1961 |
| Nationalteam1: | Czechoslovakia |
| Nationalcaps1: | 22 |
| Nationalgoals1: | 1 |
František Šafránek (2 January 1931 – 27 June 1987) was a Czech football player.
Šafránek played for several clubs, including Spartak Sokolovo (1949–1952) and Dukla Prague (1952–1966).
He played for Czechoslovakia national team (22 matches and one goal), and was a participant at the 1954 FIFA World Cup, where he played in two matches, at the 1958 FIFA World Cup, and at the 1960 UEFA European Football Championship.
He died from heart failure during the match of former Dukla Prague players in June 1987.[1]