Frank Uhlmann Explained

Alma Mater:University of Tübingen (PhD)
Thesis Title:Reconstitution and characterisation of human replication factor C
Thesis Url:https://www.worldcat.org/oclc/51443586
Thesis Year:1997

Frank Uhlmann FRS[1] is a group leader at the Francis Crick Institute in London.[2] [3] [4] [5] [6] [7]

Education

Uhlmann was educated at the University of Tübingen where he was awarded a PhD in 1997.[8] During his PhD, he worked with Jerard Hurwitz at the Memorial Sloan Kettering Cancer Center in New York City.[9] [10] [11]

Career

Following his PhD, Uhlmann moved to the Research Institute of Molecular Pathology in Vienna for postdoctoral research with Kim Nasmyth. In 2000, he established a laboratory at the Imperial Cancer Research Fund (now Cancer Research UK)[12] in London, which ultimately became part of the Francis Crick Institute.[11]

Awards and honours

Uhlmann was elected a Fellow of the Royal Society (FRS) in 2015. His certificate of election reads:

In 2006, Uhlmann was also elected a member of the European Molecular Biology Organization (EMBO)[13] and awarded the EMBO Gold Medal.

Notes and References

  1. Web site: Dr Frank Uhlmann FRS: Group Leader, The Francis Crick Institute . The Royal Society . 2015-05-02 . https://web.archive.org/web/20150502204138/https://royalsociety.org/people/fellowship/2015/frank-uhlmann/ . London.
  2. 10403247. 1999. Uhlmann. F. Sister-chromatid separation at anaphase onset is promoted by cleavage of the cohesin subunit Scc1. Nature. 400. 6739. 37–42. Lottspeich. F. Nasmyth. K. 10.1038/21831. 1999Natur.400...37U. 4354549.
  3. 11081625. 2000. Uhlmann. F . Frank Uhlmann. Cleavage of cohesin by the CD clan protease separin triggers anaphase in yeast. Cell. 103. 3. 375–86. Wernic. D. Poupart. M. A.. Koonin. E. V. . Eugene Koonin. Nasmyth. K . Kim Nasmyth . 10.1016/s0092-8674(00)00130-6. 2667617. free.
  4. 9990856. 316435. 1999. Tóth. A. Yeast cohesin complex requires a conserved protein, Eco1p(Ctf7), to establish cohesion between sister chromatids during DNA replication. Genes & Development. 13. 3. 320–33. Ciosk. R. Uhlmann. F . Frank Uhlmann. Galova. M. Schleiffer. A. Nasmyth. K . Kim Nasmyth . 10.1101/gad.13.3.320.
  5. 10827941. 2000. Nasmyth. K . Kim Nasmyth. Splitting the chromosome: Cutting the ties that bind sister chromatids. Science . New York, N.Y.. 288. 5470. 1379–85. Peters. J. M.. Uhlmann. F . Frank Uhlmann . 10.1126/science.288.5470.1379. 2000Sci...288.1379N.
  6. 25569132. 4287440. 2015. Godfrey. M. Nur1 dephosphorylation confers positive feedback to mitotic exit phosphatase activation in budding yeast. PLOS Genetics. 11. 1. e1004907. Kuilman. T. Uhlmann. F . Frank Uhlmann. 10.1371/journal.pgen.1004907. free.
  7. 25922992. 4413874. 2015. Cheng. T. M.. A simple biophysical model emulates budding yeast chromosome condensation. eLife. 4. e05565. Heeger. S. Chaleil. R. A.. Matthews. N. Stewart. A. Wright. J. Lim. C. Bates. P. A.. Uhlmann. F . Frank Uhlmann. 10.7554/eLife.05565. free.
  8. PhD . Frank. Uhlmann . Reconstitution and characterization of human replication factor C . University of Tübingen . 1997 . 51443586.
  9. 9092550. 10.1074/jbc.272.15.10065. 1997. Uhlmann. F. Identification of regions within the four small subunits of human replication factor C required for complex formation and DNA replication. The Journal of Biological Chemistry. 272. 15. 10065–71. Gibbs. E. Cai. J. O'Donnell. M. Hurwitz. J. free.
  10. 8692848. 39056. 1996. Uhlmann. F. In vitro reconstitution of human replication factor C from its five subunits. Proceedings of the National Academy of Sciences of the United States of America. 93. 13. 6521–6. Cai. J. Flores-Rozas. H. Dean. F. B.. Finkelstein. J. O'Donnell. M. Hurwitz. J . 10.1073/pnas.93.13.6521. 1996PNAS...93.6521U. free.
  11. Web site: https://web.archive.org/web/20150525162435/http://www.crick.ac.uk/research/a-z-researchers/researchers-t-u/frank-uhlmann/biography/. 2015-05-25. Frank Uhlmann biography. Francis Crick Institute. London.
  12. Web site: https://web.archive.org/web/20150527084945/http://pcc.ecmcnetwork.org.uk/cancer-info/cancerandresearch/ourcurrentresearch/researchbygrantee/dr-frank-uhlmann. 2015-05-27. Frank Uhlmann: Understanding how cells divide. Cancer Research UK.
  13. Web site: The EMBO Pocket Directory. https://web.archive.org/web/20150316002020/http://www.embo.org/documents/members/The_EMBO_Pocket_Directory.pdf. 2015-03-16. European Molecular Biology Organization.

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