| Frank Guilford | |
| State House: | Florida |
| District: | Calhoun County |
| Term Start: | November 1962 |
| Term End: | 1966 |
| Birth Date: | 1 July 1928 |
| Birth Place: | Dothan, Alabama, United States |
| Death Date: | July 27, 2020 (aged 92) |
| Death Place: | Blountstown, Florida, United States |
| Party: | Democratic |
| Occupation: | educator |
| Residence: | Blountstown, Florida |
| Alma Mater: | Florida State University |
Frank Edwin Guilford (July 1, 1928 – July 27, 2020) was a politician in the American state of Florida.[1] He served in the Florida House of Representatives from 1962 to 1966, representing Calhoun County.[2] [3]