| Frank Gregory | |
| Position: | Pitcher |
| Bats: | Right |
| Throws: | Right |
| Birth Date: | 25 July 1888 |
| Birth Place: | Spring Valley, Wisconsin |
| Death Place: | Beloit, Wisconsin |
| Debutleague: | MLB |
| Debutdate: | September 5 |
| Debutyear: | 1912 |
| Debutteam: | Cincinnati Reds |
| Finalleague: | MLB |
| Finaldate: | October 6 |
| Finalyear: | 1912 |
| Finalteam: | Cincinnati Reds |
| Statleague: | MLB |
| Stat1label: | Win–loss record |
| Stat1value: | 2–0 |
| Stat2label: | Earned run average |
| Stat2value: | 4.60 |
| Stat3label: | Strikeouts |
| Stat3value: | 4 |
| Teams: | |
Frank Ernst Gregory (July 25, 1888 – November 5, 1955) was a professional baseball player. He was a right-handed pitcher for one season (1912) with the Cincinnati Reds. For his career, he compiled a 2–0 record, with a 4.60 earned run average, and four strikeouts in 15⅔ innings pitched.
He was born in Spring Valley (town), Wisconsin and died in Beloit, Wisconsin at the age of 67.