| Honorific-Prefix: | Captain |
| Francisco de Salas | |
| Office1: | Lieutenant Governor of Buenos Aires |
| Term Start1: | 1603 |
| Term End1: | 1604 |
| Predecessor1: | Francés de Beaumont y Navarra |
| Successor1: | Manuel de Frias |
| Order3: | Mayor of Buenos Aires |
| Term Start3: | 1613 |
| Term End3: | 1614 |
| Predecessor3: | Víctor Casco de Mendoza |
| Successor3: | Juan de Vergara |
| Order4: | Vice-mayor of Buenos Aires |
| Term Start4: | 1608 |
| Term End4: | 1609 |
| Predecessor4: | Cristóbal Perez de Arostegui |
| Successor4: | Pedro Hurtado |
| Birth Name: | Francisco de Salas Videla y Reynoso |
| Birth Date: | 16th century |
| Birth Place: | Esquivias, Toledo, Spain |
| Death Date: | 17th century |
| Death Place: | Buenos Aires, Argentina |
| Spouse: | Leonor Correa de Santana |
| Signature: | Francisco de Salas, firma.jpg |
| Branch: | Spanish Army |
| Rank: | Captain |
Francisco de Salas (?-?) was a Spanish military man and politician, who served as captain, mayor, councillor, lieutenant governor, and justice major in the Ciudad de Trinidad y Puerto de Buenos Aires.
Francisco de Salas Videla Reynoso was born in Esquivias, Toledo, Spain, son of Juan de Salas and Susana de Barahona, belonging to a noble Spanish family. He was married in Buenos Aires to Leonor Correa de Santana, daughter of Pedro Correa and Antonia Moreno, natives of Andalusia. His wife was a niece of Anton Higueras de Santana, who arrived at the Río de la Plata in the expedition of Juan Ortiz de Zárate.
After settling in the Río de la Plata, Francisco de Salas served as a royal official. His first public office was perhaps as a regidor of Buenos Aires, a position he held in 1590. That same year, he was designated as fiel ejecutor (dedicated to the control of commercial activities).
In 1602 he was appointed lieutenant governor and justice major of the Río de la Plata. And in 1606 was council of the city. In 1608 he served as mayor of second vote, and was elected mayor of the first vote of the city of Buenos Aires on January 1, 1613.
Francisco Salas Reynoso held the honorary position of Alférez Real on several occasions, being in charge of carrying the royal standard, and the organization of the festival in honor of Saint Martin of Tours.