| Type: | Bishop |
| Honorific-Prefix: | Most Reverend |
| Francisco de Melo | |
| Bishop of Goa | |
| Church: | Catholic Church |
| Diocese: | Diocese of Goa |
| Term: | 1533–1536 |
| Predecessor: | None |
| Successor: | João de Albuquerque |
| Death Date: | 27 Apr 1536 |
Francisco de Melo (died 1536) was a Roman Catholic prelate who was named as the first Bishop of Goa (1533–1536).[1]
On 31 Jan 1533, Francisco de Melo was appointed during the papacy of Pope Clement VII as the first Bishop of Goa.[2] He never took possession of the diocese as he died in Evora, Portugal prior to his departure on 27 Apr 1536.[3]