| Francisco de Lersundi | |
| Office: | Prime Minister of Spain |
| Term Start: | 14 April 1853 |
| Term End: | 19 September 1853 |
| Predecessor: | Federico Roncali |
| Successor: | Luis José Sartorius |
| Birth Date: | 28 January 1817 |
| Birth Place: | Valencia, Spain |
| Death Date: | 17 November 1874 (aged 57) |
| Death Place: | Bayonne, France |
| Birthname: | Francisco de Lersundi y Ormaechea |
| Nationality: | Spanish |
| Honorific Prefix: | The Most Excellent |
| Monarch2: | Isabella II |
| Office2: | Minister of War of Spain |
| Predecessor2: | Rafael Aristégui y Vélez |
| Primeminister2: | Juan Bravo Murillo |
| Termend2: | 16 January 1852 |
| Termstart2: | 6 February 1851 |
| Successor2: | Joaquín Ezpeleta Enrile |
| Monarch3: | Isabella II |
| Predecessor3: | Juan de Lara |
| Successor3: | Anselmo Blaser |
| Termstart3: | 14 April |
| Termend3: | 19 September 1853 |
| Primeminister3: | Himself |
| Monarch4: | Isabella II |
| Predecessor4: | José Gutiérrez de la Concha |
| Successor4: | José María Marchessi y Oleaga |
| Termstart4: | 17 January |
| Termend4: | 1 March 1864 |
| Primeminister4: | Lorenzo Arrazola |
| Office5: | Minister of the Navy of Spain |
| Monarch5: | Isabella II |
| Primeminister5: | Ramón María Narváez |
| Predecessor5: | Pedro Bayarri |
| Successor5: | José María de Bustillo Gómez de Barreda |
| Office6: | Governor of Cuba |
| Monarch6: | Isabella II |
| Monarch7: | Isabella II |
| Termstart5: | 12 October |
| Termend5: | 15 October 1856 |
| Termstart6: | 30 May |
| Termend6: | 3 November 1866 |
| Termstart7: | 21 December 1867 |
| Termend7: | 4 January 1869 |
| Predecessor6: | Domingo Dulce |
| Successor6: | Joaquín del Manzano |
| Predecessor7: | Blas Villate |
| Successor7: | Domingo Dulce |
| 1Blankname6: | Minister of Overseas |
| 1Blankname7: | Regent |
| 1Namedata6: | Antonio Cánovas del Castillo Alejandro de Castro y Casal |
| 1Namedata7: | Francisco Serrano |
| 2Blankname7: | Prime Minister |
| 2Namedata7: | Luis González Bravo José Gutiérrez de la Concha Francisco Serrano |
| Primeminister6: | Leopoldo O'Donnell Ramon María Narváez |
| 3Blankname7: | Minister of Overseas |
| 3Namedata7: | Carlos Marfori y Callejas Tomás Rodríguez Rubí José Nacarino Bravo (as interim) Adelardo López de Ayala |
Francisco de Lersundi y Hormaechea (28 January 1817 in Valencia, Spain[1] – 17 November 1874 in Bayonne, France[2]) was a Spanish noble and politician who served as Prime Minister of Spain in 1853 and held other important offices such as Captain General of Cuba from 1866 to 1869. While he served as Prime Minister, he also simultaneously was the Minister of War.[3]
He was appointed a senator for life in 1853.[4]