| Francisco Romero Portilla | |
| Nationality: | Guatemalan |
| Sport: | Sports shooting |
| Birth Date: | 27 May 1931 |
Francisco Romero Portilla (27 May 1931 – 13 August 2022) was a Guatemalan former sports shooter. He competed in the mixed trap event at the 1980 Summer Olympics.[1] He was 49 years old at the time, making him the oldest Olympian to represent Guatemala. His son Francisco Romero Arribas was also an Olympic sport shooter.[2]