| Francisco de Lersundi | |
| Office: | Prime Minister of Spain |
| Term Start: | 14 April 1853 |
| Term End: | 19 September 1853 |
| Predecessor: | Federico Roncali |
| Successor: | Luis José Sartorius |
| Birth Date: | 28 January 1817 |
| Birth Place: | Valencia, Spain |
| Death Date: | 17 November 1874 (aged 57) |
| Death Place: | Bayonne, France |
| Birthname: | Francisco de Lersundi y Ormaechea |
| Nationality: | Spanish |
| Honorific Prefix: | The Most Excellent |
Francisco de Lersundi y Hormaechea (28 January 1817 in Valencia, Spain[1] – 17 November 1874 in Bayonne, France[2]) was a Spanish noble and politician who served as Prime Minister of Spain in 1853 and held other important offices such as Captain General of Cuba from 1866 to 1869. While he served as Prime Minister, he also simultaneously was the Minister of War.[3]
He was appointed a senator for life in 1853.[4]