| Francisco José Urrutia Holguín | |
| Order2: | 11th |
| Ambassador From2: | Colombia |
| Country2: | United States |
| Term Start2: | 14 November 1955 |
| Term End2: | 10 October 1957 |
| Predecessor2: | Eduardo Zuleta Ángel |
| Successor2: | José Gutiérrez Gómez |
| President2: | Gustavo Rojas Pinilla |
| Order3: | 7th |
| Office3: | Permanent Representative of Colombia to the United Nations |
| Term Start3: | 19 August 1953 |
| Term End3: | 4 September 1957 |
| President3: | Gustavo Rojas Pinilla |
| Predecessor3: | Evaristo Sourdis Juliao |
| Successor3: | Alfoso Araújo |
| Ambassador From4: | Colombia |
| Country4: | Venezuela |
| Term Start4: | 1952 |
| Term End4: | 1953 |
| President4: | Roberto Urdaneta Arbeláez |
| Ambassador From5: | Colombia |
| Country5: | Argentina |
| Term Start5: | 1948 |
| Term End5: | 1950 |
| President5: | Mariano Ospina Pérez |
| Birth Date: | 28 May 1910 |
| Birth Place: | Quito, Pichincha, Ecuador |
| Death Place: | Bogotá, D.C., Colombia |
| Nationality: | Colombian-Ecuadorian |
| Spouse: | Genoveva Montoya Williamson (1934-) |
| Children: | Francisco Antonio Urrutia Montoya María Lourdes Urrutia Montoya Jorge Urrutia Montoya Miguel Urrutia Montoya Jaime Urrutia Montoya |
| Alma Mater: | National University of Colombia (PhD) |
| Profession: | Lawyer |
Francisco José Urrutia Holguín (28 May 1910 - 19 October 1981) was a Colombian-Ecuadorian lawyer and diplomat. He served as the seventh Permanent Representative of Colombia to the United Nations, the 11th Colombia Ambassador to United States, and the Ambassador to Venezuela and Argentina.
Francisco José Urrutia Holguín was born on 28 May 1910 in Quito, Ecuador to Francisco José Urrutia Olano, a Colombian diplomat who served as Minister of Foreign Affairs, and Minister Plenipotentiary of Colombia in Ecuador, and Elena Holguín Arboleda, Colombian activist who served as President of the Anti-Tuberculosis League of Colombia, and President of the Colombian Red Cross. He married Genoveva Montoya Williamson on 18 July 1934 in Bogotá, and together had five children: Francisco, María Lourdes, Jorge, Miguel, and Jaime.[1]