| Francisco Frione | |
| Birth Date: | 21 July 1912 |
| Birth Place: | Montevideo, Uruguay |
| Death Place: | Milan, Italy |
| Position: | Midfielder |
| Years1: | 1931–1932 |
| Years2: | 1932–1935 |
| Clubs2: | Ambrosiana-Inter |
| Caps2: | 54 |
| Goals2: | 12 |
| Nationalteam1: | Uruguay |
| Nationalcaps1: | 6 |
| Nationalgoals1: | 0 |
Francisco Frione, also known as Francesco Frione (21 July 1912 – 17 February 1935), was an Uruguayan-Italian professional football player. He was born in Uruguay and played for the Uruguay national football team, but later was naturalized as an Italian citizen and played for the Italian national B team.
Frione's family was of Ligurian descent, from the city of Finale Ligure.[1] [2]
Frione scored 7 goals in 20 appearances for Montevideo Wanderers F.C. before moving to Italy in 1932.[3]
His older brother Ricardo Alberto Frione also played football professionally. To distinguish them, Ricardo Alberto was referred to as Frione I and Francisco as Frione II.