| Francis O'Beirne | |
| Office: | Member of Parliament for Leitrim |
| Term Start: | 14 July 1876 |
| Term End: | 24 November 1885 |
| Predecessor: | John Brady William Ormsby-Gore |
| Alongside: | Arthur Loftus Tottenham (1885 – 1880) John Brady (1876 – 1880) |
| Successor: | Constituency abolished |
| Birth Date: | 1833 |
| Nationality: | Irish |
| Party: | Home Rule League |
Francis O'Beirne (1833 – 11 April 1899) was an Irish Home Rule League politician. He served as a Member of Parliament (MP) for Leitrim from 1876 to 1885.
He first stood for election in Leitrim in 1874 but was unsuccessful. He was then elected at a by-election in 1876 and held the seat until it was abolished in 1885.[1]