| Pre-Nominals: | Sir |
| Post-Nominals: | MP |
| Francis Godolphin | |
| Death Date: | 2 May 1640 |
| Nationality: | English |
| Occupation: | Politician and Knight |
| Sir | |
| Parents: | Sir Francis Godolphin (1540–1608) Margaret Killigrew |
Sir Francis Godolphin (died 1640) was an English nobleman, politician, knight, and Member of Parliament.
Godolphin was the third son of Sir Francis Godolphin (1540–1608) and his first wife Margaret Killigrew. He represented St Ives in the Parliaments of 1624–5 and 1625, and Cornwall in that of 1626. He was also Recorder of Helston in 1620. He was still alive in 1637, and his will was proved on 2 May 1640.