| Francis B. De Witt | |
| State: | Ohio |
| Term Start: | March 4, 1895 |
| Term End: | March 3, 1897 |
| Preceded: | Dennis D. Donovan |
| Succeeded: | David Meekison |
| Party: | Republican |
| Restingplace: | Live Oak Cemetery, Paulding, Ohio |
| Death Place: | Standish, Michigan |
| Birth Place: | Jackson County, Indiana |
| Birth Date: | 11 March 1849 |
| Alma Mater: | |
| Allegiance: | United States |
| Branch: | Union Army |
| Unit: | |
| Battles: | American Civil War |
Francis Byron De Witt (March 11, 1849 – March 21, 1929) was a U.S. Representative from Ohio for one term from 1895 to 1897.
Born in Jackson County, Indiana, De Witt moved with his parents in 1854 to a farm in Delaware County, Ohio.During the Civil War enlisted in the Forty-sixth Regiment, Ohio Volunteer Infantry, at the age of twelve.Mustered out for temporary disability and reenlisted in 1862 in the One Hundred and Twenty-first Regiment, Ohio Volunteer Infantry, and served until the close of the war.Prisoner of war in Salisbury, Danville, and Libby Prisons.He attended the common schools and high school in Galena, Ohio, National Normal School, Lebanon, Ohio, and Ohio Wesleyan University, Delaware, Ohio.He moved to Paulding, Ohio, in 1872 and taught school.He studied law.He was admitted to the bar in 1875 and practiced his profession in Paulding until 1891, when he engaged in agricultural pursuits.He served as member of the State house of representatives 1892-1895.
De Witt was elected as a Republican to the Fifty-fourth Congress (March 4, 1895 – March 3, 1897).He was an unsuccessful candidate for reelection in 1896.
He resumed agricultural pursuits near Paulding, Ohio.He moved to Standish, Michigan, in 1903 and resumed the practice of law.He served as register of deeds.He served as member of the Michigan House of Representatives 1920-1922.
De Witt was elected prosecuting attorney of Arenac County, Michigan, in 1926.He was reelected in 1928 and served until his death in Standish, Michigan, on March 21, 1929.He was interred in Live Oak Cemetery, Paulding, Ohio.