| Type: | Bishop |
| Honorific-Prefix: | Most Reverend |
| Francesco Maria Giannotti | |
| Bishop of Segni | |
| Church: | Catholic Church |
| Diocese: | Diocese of Segni |
| Term: | 1682–1699 |
| Predecessor: | Guarnerio Guarnieri |
| Successor: | Orazio Minimi |
| Ordination: | 1 May 1682 |
| Consecration: | 14 June 1682 |
| Birth Date: | 1635 |
| Birth Place: | Rome, Italy |
| Death Date: | April 1699 |
| Death Place: | Segni, Italy |
| Nationality: | Italian |
Francesco Maria Giannotti (1635 – April, 1699) was a Roman Catholic prelate who served as Bishop of Segni (1682–1699).
Francesco Maria Giannotti was born in Rome, Italy in 1635, He was ordained a deacon on 26 April 1682 and as a priest on 1 May 1682. On 4 May 1682, he was appointed during the papacy of Pope Innocent XI as Bishop of Segni. On 14 June 1682, he was consecrated bishop. He served as Bishop of Segni until his death in April 1699.
While bishop, he was the principal co-consecrator of: