| Honorific-Prefix: | Most Reverend |
| Francesco Antonio Balduini | |
| Bishop of Alessano | |
| Church: | Catholic Church |
| Diocese: | Diocese of Alessano |
| Term: | 1531–1539 |
| Predecessor: | Alessandro Cesarini |
| Successor: | Benedetto de Sanctis |
| Death Date: | 1539 |
| Death Place: | Alessano, Italy |
Francesco Antonio Balduini (died 1539) was a Roman Catholic prelate who served as Bishop of Alessano (1531–1539).[1]
On 15 November 1531, Francesco Antonio Balduini was appointed during the papacy of Pope Clement VII as Bishop of Alessano. He served as Bishop of Alessano until his death in 1539.