| Francis de Bourbon | |
| Count of Vendôme | |
| Father: | John VIII, Count of Vendôme |
| Mother: | Isabelle de Beauvau |
| Spouse: | Marie of Luxembourg |
| Issue: | Charles, Duke of Vendôme Francis, Count of Saint-Pol Louis, Archbishop of Sens Antoinette, Duchess of Guise Louise, Abbess of Fontevraud |
| Birth Date: | c. 1470 |
| Birth Place: | Vendôme, Loir-et-Cher, France. |
| Death Place: | Vercelli, Piedmont, Italy. |
Francis of Bourbon or François de Bourbon, (c. 1470 – 30 October 1495), was the Count of Vendôme and a French prince du sang.
Francis was the son of John VIII de Bourbon, Count of Vendôme and Isabelle de Beauvau, the daughter of Louis de Beauvau, Marshal of Provence. As a legitimate member of the Capetian dynasty, he ranked in France as a prince du sang. Francis was seven, when his father died and he succeeded as count of Vendôme. During his minority, his estates were administered by his brother in law, Louis of Joyeuse.
In 1487, Francis married Marie of Luxembourg, the elder daughter and principal heiress of Peter II of Luxembourg, Count of Saint-Pol and Soissons, and Margaret of Savoy. She brought great estates as her dowry, including the countships of Saint-Pol and Soissons in Picardy, as well as the Château de Condé.
Francis and Marie conceived:
By Isabeau de Grigny, Francis had an illegitimate son:
Francis de Bourbon died at the age of 25 in Vercelli, Italy, and was succeeded by his eldest son, Charles IV de Bourbon. His widow Marie administered the family's estates during Charles' minority.