| François D'Onofrio | |
| Birth Date: | 6 October 1990 |
| Birth Place: | Liège, Belgium |
| Position: | Defender |
| Youthyears1: | 2008–2009 |
| Youthclubs1: | Standard Liège |
| Years1: | 2009–2011 |
| Years2: | 2010 |
| Clubs2: | Standard Liège |
| Caps2: | 1 |
| Goals2: | 0 |
| Years3: | 2012–2013 |
| Caps3: | 6 |
| Goals3: | 0 |
| Years4: | 2014–2016 |
| Caps4: | 41 |
| Goals4: | 1 |
| Years5: | 2016–2017 |
| Caps5: | 0 |
| Goals5: | 0 |
| Years6: | 2018–2020 |
| Clubs6: | Lierse Kempenzonen |
| Caps6: | 20 |
| Goals6: | 0 |
| Years7: | 2020–2022 |
| Caps7: | 8 |
| Goals7: | 0 |
François D'Onofrio (born 6 October 1990), also known as Francesco D'Onofrio, is a Belgian former professional footballer. He also holds Italian citizenship.
He made his professional debut in the Belgian First Division A for Standard Liège on 27 November 2010 in a game against Lierse.[1]
In the summer 2018, D'Onofrio joined Lierse Kempenzonen.[2] In January 2020, he was sent down to Lierse's B-team alongside Kassim Doumbia.[3]
D'Onofrio retired from playing in November 2022.[4]