| François Byssot de la Rivière | |
| Birth Date: | 1612 or 1613 |
| Birth Place: | Pont-Audemer, France |
| Death Date: | 26 July 1673 |
| Death Place: | Quebec, Canada |
| Parents: | Jean Byssot Du Hommée Marie Assour |
François Byssot de la Rivière (1612–1673) was an early figure in the New World, his presence being recorded at Île-aux-Ruaux in 1639 when the Jesuits took possession of the property. He married Marie Couillard in Quebec on 25 October 1648.
Byssot was active in a number of pursuits and his name is associated with some of the earliest land grants and was also a person of note in seigneurial justice. In 1661, he received, from the Compagnie des Cent-Associés, a concession in what is now Labrador. He may have constructed a post at Mingan. He constructed the first tannery and was granted some other important concessions in both fishing and harvesting seals.
He had twelve children, two of whom, Jean-Baptiste and François-Joseph, attained some notability in Canadian history.