| Cabinet Name: | Depretis IV government |
| Cabinet Number: | 21st |
| Jurisdiction: | Italy |
| Flag: | Flag of Italy (1861-1946).svg |
| Flag Border: | true |
| Date Formed: | 29 May 1881 |
| Date Dissolved: | 25 May 1883 |
| Government Head: | Agostino Depretis |
| State Head: | Umberto I |
| Total Number: | 10 |
| Political Party: | Historical Left |
| Previous: | Cairoli III Cabinet |
| Successor: | Depretis V Cabinet |
The Depretis IV government of Italy held office from 29 May 1881 until 25 May 1883, a total of 726 days, or 1 year, 11 months and 26 days.[1]
The government was composed by the following parties:
| Office | Name | Party | Term | ||
|---|---|---|---|---|---|
| Prime Minister | Agostino Depretis | Historical Left | (1881–1883) | ||
| Minister of the Interior | Agostino Depretis | Historical Left | (1881–1883) | ||
| Minister of Foreign Affairs | Pasquale Stanislao Mancini | Historical Left | (1881–1883) | ||
| Minister of Grace and Justice | Giuseppe Zanardelli | Historical Left | (1881–1883) | ||
| Minister of Finance | Agostino Magliani | Historical Left | (1881–1883) | ||
| Minister of Treasury | Agostino Magliani | Historical Left | (1881–1883) | ||
| Minister of War | Emilio Ferrero | Military | (1881–1883) | ||
| Minister of the Navy | Ferdinando Acton | Military | (1881–1883) | ||
| Minister of Agriculture, Industry and Commerce | Domenico Berti | Historical Left | (1881–1883) | ||
| Minister of Public Works | Alfredo Baccarini | Historical Left | (1881–1883) | ||
| Minister of Public Education | Guido Baccelli | Historical Left | (1881–1883) | ||