Foscarbidopa Explained
Foscarbidopa is a drug which acts as a prodrug for carbidopa. It is used in a subcutaneous infusion as a fixed-dose combination with foslevodopa for the treatment of Parkinson's disease, under the trade name Vyalev.[1] [2]
Notes and References
- Poplawska-Domaszewicz K, Batzu L, Falup-Pecurariu C, Chaudhuri KR . Subcutaneous Levodopa: A New Engine for the Vintage Molecule . Neurology and Therapy . 13 . 4 . 1055–1068 . August 2024 . 38874708 . 10.1007/s40120-024-00635-4 . 11263521 .
- Fung VS, Aldred J, Arroyo MP, Bergquist F, Boon AJ, Bouchard M, Bray S, Dhanani S, Facheris MF, Fisseha N, Freire-Alvarez E, Hauser RA, Jeong A, Jia J, Kukreja P, Soileau MJ, Spiegel AM, Talapala S, Tarakad A, Urrea-Mendoza E, Zamudio J, Pahwa R . Continuous subcutaneous foslevodopa/foscarbidopa infusion for the treatment of motor fluctuations in Parkinson's disease: Considerations for initiation and maintenance . Clinical Parkinsonism & Related Disorders . 2024 . 10 . 100239 . 38419617 . 10.1016/j.prdoa.2024.100239 . 10900117 .