Michelin tire baby syndrome explained

Michelin tire baby syndrome
Field:	dermatology

Michelin tire baby syndrome (also known as Kunze–Riehm syndrome^[1] and "folded skin with scarring"^[2]), is a condition occurring in babies that is characterized by multiple, symmetric, circular skin creases, or bands, on the forearms, lower legs, and often the neck that are present at birth. The creases disappear later in life. They are reminiscent of those of Bibendum, the mascot of the tire manufacturer Michelin, hence the name of the syndrome. Associated abnormalities vary and may include facial dysmorphism, upslanting palpebral fissures, hypertelorism, cleft palate, genital anomalies, mild developmental delay, ureterocele, smooth muscle hamartoma, nevus lipomatosus, Laron syndrome (dwarfism with high growth hormone and low somatomedin activity), and other defects.

It was originally described by Ross in 1969.^[3]

See also

• List of cutaneous conditions

References

• Bass HN, Caldwell S, Brooks BS . Michelin tire baby syndrome: familial constriction bands during infancy and early childhood in four generations . Am J Med Genet . 45 . 3 . 370–2 . February 1993 . 8434626 . 10.1002/ajmg.1320450318.
• Schnur RE, Herzberg AJ, Spinner N, etal . Variability in the Michelin tire syndrome. A child with multiple anomalies, smooth muscle hamartoma, and familial paracentric inversion of chromosome 7q . J Am Acad Dermatol . 28 . 2 Pt 2 . 364–70 . February 1993 . 8436660 . 10.1016/0190-9622(93)70056-Y.
• . Circumferential ringed creases ('Michelin tire babies') with specific histologic findings and/or karyotype abnormalities: clues to molecular pathogenesis? . Am J Med Genet . 69 . 2 . 221 . March 1997 . 9056567 . 10.1002/(SICI)1096-8628(19970317)69:2<221::AID-AJMG22>3.0.CO;2-M.
• Pivnick EK, Wilroy RS, Martens PR, Teather TC, Hashimoto K . Hypertrichosis, pigmentary retinopathy, and facial anomalies: a new syndrome? . Am J Med Genet . 62 . 4 . 386–90 . April 1996 . 8723069 . 10.1002/(SICI)1096-8628(19960424)62:4<386::AID-AJMG11>3.0.CO;2-K .
• Oku T, Iwasaki K, Fujita H . Folded skin with an underlying cutaneous smooth muscle hamartoma . Br J Dermatol . 129 . 5 . 606–8 . November 1993 . 8251362 . 10.1111/j.1365-2133.1993.tb00495.x. 34499359 .

External links

• DermAtlas images

Notes and References

1. Ramphul. Kamleshun. Mejias. Stephanie G. Ramphul-Sicharam. Yogeshwaree. A Rare Case of Michelin Tire Baby Syndrome in a Newborn. Cureus. 2018. 10. 2. e2222. 10.7759/cureus.2222. free . 2168-8184. 5914916. 29696100.
2. James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. .
3. Ross CM . Generalized folded skin with an underlying lipomatous nevus. "The Michelin Tire baby" . Arch Dermatol . 100 . 3 . 320–3 . September 1969 . 4980758 . 10.1001/archderm.100.3.320 .