Folch solution explained

A Folch solution is a solution containing chloroform and methanol, usually in a 2:1 (vol/vol) ratio.[1] One of its uses is in separating polar from nonpolar compounds, for example separating nonpolar lipids from polar proteins and carbohydrates in blood serum.

Notes and References

  1. Folch. J.. Lees. M.. Sloan Stanley. G.H.. A Simple Method for the Isolation and Purification of Total Lipides from Animal Tissues. Journal of Biological Chemistry. May 1, 1957. 226. 497–509. 10.1016/S0021-9258(18)64849-5. free.

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