Fluorenone Explained

Fluorenone is an organic compound with the chemical formula . It is bright fluorescent yellow solid.

Synthesis and reactions

It is synthesised by aerobic oxidation of fluorene:[1]

Fluorenone sustains up to four nitro groups giving 2,4,5,7-tetranitrofluorenone.[2]

Applications

Several substituted fluorenones are biologically active as antibiotic, anticancer, antiviral, or neuromodulatory compounds.[3]

Some substituted azafluorenones are biologically active, such as the naturally occurring antimicrobial compound onychine (1-methyl-4-azafluorenone).[4] The compound 1,8-diazafluoren-9-one is used for fingerprint detection.

See also

External links

Notes and References

  1. Encyclopedia: Karl Griesbaum . Arno Behr . Dieter Biedenkapp . Heinz-Werner Voges . Dorothea Garbe . Christian Paetz . Gerd Collin . Dieter Mayer . Hartmut Höke . Hydrocarbons. Ullmann's Encyclopedia of Industrial Chemistry. 2002. Wiley-VCH. Weinheim. 10.1002/14356007.a13_227. 3-527-30673-0.
  2. 10.15227/orgsyn.042.0095. 2,4,5,7-Tetranitrofluorenone . Organic Syntheses . 1962 . 42 . 95. Melvin S. Newman and H. Boden .
  3. Patel . Sagarkumar . Rathod . Bhagyashri . Regu . Siddulu . Chak . Shivam . Shard . Amit . A Perspective on Synthesis and Applications of Fluorenones . . 5 . 34 . 2020 . 2365-6549 . 10.1002/slct.202002695 . 10673–10691. 224995927 .
  4. Gomes . Claudia R.B. . de Souza . Marcus V.N. . Facchinetti . Victor . A Review on Onychine and its Analogs: Synthesis and Biological Activity . Current Organic Synthesis . 17 . 1 . 2020-02-24 . 1570-1794 . 10.2174/1570179417666191218112842 . 3–22. 32103713 . 211535420 .

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Fluorenone".

Except where otherwise indicated, Everything.Explained.Today is © Copyright 2009-2024, A B Cryer, All Rights Reserved. Cookie policy.