Fluminorex Explained

Fluminorex is a centrally acting sympathomimetic which is related to other drugs such as aminorex and pemoline. It was developed as an appetite suppressant by McNeil Laboratories in the 1950s.^{[1] [2]}

Synthesis

2-amino-1-[4-(trifluoromethyl)phenyl]ethanol [776-02-3] (1)cyanogen bromide [506-68-3] (2)

See also

• 4'-Fluoro-4-methylaminorex
• 4-Methylaminorex
• Aminorex
• Clominorex
• Cyclazodone
• Fenozolone
• Pemoline
• Thozalinone

Notes and References

1. US Patent 3278382 - 2-amino-5-aryloxazoline compositions and methods of using same
2. Maier J, Mayer FP, Brandt SD, Sitte HH . DARK Classics in Chemical Neuroscience: Aminorex Analogues . ACS Chemical Neuroscience . 9 . 10 . 2484–2502 . October 2018 . 10.1021/acschemneuro.8b00415 . 30269490 . 6287711 .