| Official Name: | Florentino Ameghino |
| Pushpin Map: | Argentina |
| Pushpin Label Position: | bottom |
| Pushpin Map Caption: | Location in Argentina |
| Pushpin Mapsize: | 200 |
| Pushpin Mapsize1: | 200 |
| Subdivision Type: | Country |
| Subdivision Type1: | Province |
| Subdivision Name1: | Buenos Aires |
| Subdivision Type2: | Partido |
| Subdivision Name2: | Florentino Ameghino |
| Established Title: | Founded |
| Established Date: | July 10, 1910 |
| Population Total: | 6,217 |
| Coordinates: | -34.8167°N -89°W |
| Elevation M: | 100 |
| Postal Code Type: | CPA Base |
| Postal Code: | B 6064 |
| Area Code: | +54 3388 |
Florentino Ameghino is a town in Buenos Aires Province, Argentina. It is the administrative seat of the Florentino Ameghino Partido.
The town is named after Argentine naturalist, paleontologist, anthropologist and zoologist Florentino Ameghino.