Flavone Explained

Flavone is an organic compound with the formula . A white solid, flavone is a derivative of chromone with a phenyl (Ph) substituent adjacent to the ether group. The compound is of little direct practical importance, but susbstituted derivatives, the flavones and flavonoids are a large class of nutritionally important natural products.[1] Flavone can be prepared in the laboratory by cyclization of 2-hydroxacetophenone.[2] Isomeric with flavone is isoflavone, where the phenyl group is adjacent to the ketone.

References

  1. 10.1021/cr400265z. Chromone: A Valid Scaffold in Medicinal Chemistry . 2014 . Gaspar . Alexandra . Matos . Maria João . Garrido . Jorge . Uriarte . Eugenio . Borges . Fernanda . Chemical Reviews . 114 . 9 . 4960–4992 .
  2. 10.15227/orgsyn.032.0072. Flavone . Organic Syntheses . 1952 . 32 . 72. T. S. Wheeler .