The First Secretary of the Central Committee of the Communist Party of Latvia was the leader of the Communist Party of Latvia, which was in turn a branch of the Communist Party of the Soviet Union.
Below is a list of office-holders:
| Name | Entered office | Left office | |
|---|---|---|---|
| Jānis Kalnbērziņš[1] | August 25, 1940 | November 25, 1959 | |
| Arvīds Pelše | November 25, 1959 | April 15, 1966 | |
| Augusts Voss | April 15, 1966 | April 14, 1984 | |
| Boris Pugo | April 14, 1984 | October 4, 1988 | |
| Jānis Vagris | October 4, 1988 | April 7, 1990 | |
| Alfrēds Rubiks | April 7, 1990 | August 24, 1991 |