| First Presbyterian Church | |
| Location: | 101 S. Plymouth Ave., Rochester, New York |
| Coordinates: | 43.1528°N -77.6156°W |
| Built: | 1871 |
| Architect: | Warner, Andrew J. |
| Architecture: | Gothic |
| Added: | October 25, 1973 |
| Area: | less than one acre |
| Refnum: | 73001202 |
First Presbyterian Church is a historic Presbyterian church located at Rochester in Monroe County, New York. It is a Gothic Revival–style edifice designed in 1871 by Rochester architect Andrew Jackson Warner. It is built of Albion sandstone and trimmed with white Medina sandstone. It features a single stone bell tower and spire at the northeast corner beside the main entrance. It was the third home for Rochester's oldest congregation.[1] It is now home to the Central Church of Christ.
It was listed on the National Register of Historic Places in 1973.